Colorado’s business climate is back under the microscope as new numbers land on lawmakers’ desks and in corporate boardrooms. A fresh chamber analysis, backed up by local reporting, links rising regulation to a wave of company exits and job losses, setting up an early fight at the Capitol as another packed legislative season kicks off.
The Colorado Chamber of Commerce’s 2025 Regulatory Landscape Update tallies more than 205,000 state-level business restrictions on the books at the end of 2025 and ranks Colorado as the sixth-most-regulated state, according to the Colorado Chamber of Commerce. The chamber’s modeling suggests that a 10% increase in regulations could translate to roughly 36,000 fewer jobs and 9,000 fewer firms.
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